Zuclopenthixol MA-Quetiapine

Zuclopenthixol
Medium long acting
Type Antipsychotic
Group Thioxanthenes
links
PubChem 5311507
PubMed Zuclopenthixol
Kompas (Dutch) Zuclopenthixol
Wikipedia Zuclopenthixol
Quetiapine
Type antipsychotic
Group atypical AP
Other use moodstabilizer
links
ATC-code N05AH04
Medscape Quetiapine
PubChem 5002
PubMed Quetiapine
Drugs.com quetiapine-fumarate
Kompas (Dutch) Quetiapine
Wikipedia Quetiapine

Switch medication from Zuclopenthixol_MA to Quetiapine.

Nietinrijdenbord.png Stop Zuclopenthixol_MA
  • Day 1: Last depot injection
Eenrichtingbord.png Start Quetiapine
  • Day 3-6: approx. 25% of target dose
  • Day 7-10: approx. 50% of target dose
  • Day 11-14: approx. 75% of target dose
  • Day 15: target dose
Infobord.png More information
  • During this switch you could monitor ECG, especially in patients prone to QT-conduction problems.
  • There is a possibility of QT interval prolongation.[5]
  • Zuclopenthixol_MA = Zuclopenthixol acetate [6]
    StopDepotZucloMAStartOral.jpg
Nietinrijdenbord.png — Zuclopenthixol_MA
Eenrichtingbord.png — Quetiapine


  1. ↑ 1.01.11.2 KNMP; Informatorium Medicamentorum 2015; Monografie "quetiapine" (Dutch)
  2. ↑ NVZA; Toxicology.org; Monografie 73 (dutch)
  3. ↑ Woods SW Chlorpromazine equivalent doses for the newer atypical antipsychotics J Clin Psychiatry 2003;64:663-667
  4. ↑ Drugs.com quetiapine-fumarate
  5. ↑ Stöllberger C, Huber JO, Finsterer J, Antipsychotic drugs and QT prolongation. Int Clin Psychopharmacol. 2005 Sep;20(5):243-51.
  6. ↑ SPC Zuclopenthixol acetate
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