- Day 1: simultaneously start administration of agomelatine in a dosage of 25 mg/day.
- If necessary, increase dosage of agomelatine to 50 mg/day.
- Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
- Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
- CBG meb, accessed june 2023, SmPC Vortioxetine
- Multidisciplinair document Afbouwen Overige Antidepressiva 2023
- McAllister-Williams RH et al. The use of antidepressants in clinical practice: focus on agomelatine. Hum Psychopharmacol. 2010 Mar 1;25(2):95-102
- Katona et al. New generation multi-modal antidepressants: focus on vortioxetine for major depressive disorder. 2014 2014 Feb 19;10:349-54
- KNMP; Informatorium Medicamentorum 2023; Monografie "vortioxetine" (Dutch)
- Summary of Product Characteristics Vortioxetine
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