Switch medication from tranylcypromine to sertraline.
- Day 1-14: decrease the original dose with about 25% every 3 days.
- Day 28: Start and increase the dose with about 50% of the target dose per week. 
- After the last dose of tranylcypromine it takes about 14 days to restore the activity of the MAO enzymes
- Occurrence of the serotonin syndrome is possible without this wash-out period.
- KNMP; Informatorium Medicamentorum 2015; Monografie "tranylcypromine" (Dutch)
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