- In general after long-term maintenance treatment, the best is to reduce the dose by about 25% every 4-6 weeks. An apt pharmaceutical dose (tablet, capsule, mixture) is not always available. In these cases one should be creative with dosing.
- Another, more risky, possibility is being at a certain dose to use the following scheme:
- 45 mg/day :
- Day 1: reduce dosage of mirtazepine to 30 mg/day.
- Day 15: reduce dosage of mirtazepine to 15 mg/day.
- Day 29: stop the administration of mirtazepine.
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