Sertindole-Rest AP

Sertindole
Type Antipsychotic
Group Atypical AP
links
PubChem 60149
PubMed Sertindole
Kompas (Dutch) Sertindole
Wikipedia Sertindole
Rest anti-psychotics

Chlorprothixene
Flupentixol
Loxapine
Paliperidone
Pericyazine
Perphenazine
Trifluoperazine
Zuclopenthixol

Switch medication from Sertindole to Rest AP.

Nietinrijdenbord.png Stop Sertindole
  • Day 1-4: approx. 75% of initial dose
  • Day 5-8: approx. 50% of initial dose
  • Day 9-12: approx. 25% of initial dose
  • Day 13: stop
Eenrichtingbord.png Start Rest AP
  • Day 1-4: approx. 25% of target dose
  • Day 5-8: approx. 50% of target dose
  • Day 9-12: approx. 75% of target dose
  • Day 13: target dose
Infobord.png More information
  • During this switch you could monitor ECG, especially in patients prone to QT-conduction problems.
  • There is a possibility of QT interval prolongation.[1]
    Switchstandaardup en down.jpg
Nietinrijdenbord.png — Sertindole
Eenrichtingbord.png — Rest AP


  1. ↑ Stöllberger C, Huber JO, Finsterer J, Antipsychotic drugs and QT prolongation. Int Clin Psychopharmacol. 2005 Sep;20(5):243-51.
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