Risperidone-Risperidone LA
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Switch medication from Risperidone to Risperidone_LA.
Stop Risperidone
- Day 1-14: Continue drug at usual dose
- Day 15-18: approx. 75% of initial dose
- Day 19-22: approx. 50% of initial dose
- Day 23-27: approx. 25% of initial dose
- Day 28: stop
Start Risperidone_LA
- Day 1: Start depot according general dosing advice (Dotted line in graph)
More information
- During this switch you could monitor ECG, especially in patients prone to QT-conduction problems.
- There is a possibility of QT interval prolongation.[4]
— Risperidone
— Risperidone_LA
— Risperidone_LA
- ↑ 1.01.1 KNMP; Informatorium Medicamentorum 2015; Monografie "risperidon" (Dutch)
- ↑ Woods SW; Chlorpromazine equivalent doses for the newer atypical antipsychotics J Clin Psychiatry 2003;64:663-667
- ↑ 3.03.1 The Lundbeck Institute; Psychotropics; Terminal Plasma Half-lives
- ↑ Stöllberger C, Huber JO, Finsterer J, Antipsychotic drugs and QT prolongation. Int Clin Psychopharmacol. 2005 Sep;20(5):243-51.
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