Rest AP-Penfluridol

Rest anti-psychotics

Chlorprothixene
Flupentixol
Loxapine
Pericyazine
Perphenazine
Trifluoperazine
Ziprasidone
Zuclopenthixol

Penfluridol
Type Antipsychotic
Group Atypical AP
links
PubMed Penfluridol
Wikipedia Penfluridol

Switch medication from Rest AP to Penfluridol.

Nietinrijdenbord.png Stop Rest AP
  • Day 1-4: approx. 75% of initial dose
  • Day 5-8: approx. 50% of initial dose
  • Day 9-12: approx. 25% of initial dose
  • Day 13: stop
Eenrichtingbord.png Start Penfluridol
  • Week 1: start with 10 mg
  • Week 2: increase dose to 20 mg
  • Week 3 and further: adjust dose according to clinical presentation
Infobord.png More information
  • During this switch you could monitor ECG, especially in patients prone to QT-conduction problems.
  • There is a possibility of QT interval prolongation.[1]
  1. Stöllberger C, Huber JO, Finsterer J, Antipsychotic drugs and QT prolongation. Int Clin Psychopharmacol. 2005 Sep;20(5):243-51.
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