Switch medication from Partial agonist to Quetiapine.
Partial agonist is a collection of antipsychotic drugs having similar properties with respect to switching. A switch to member of the 'partial agonist' group from anotherdrug should be read as partial agonist-anotherdrug. Similarly, a switch from a member of the 'partial agonist' group to anotherdrug should be read as anotherdrug-partial agonist.
Stop Partial agonist
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Day 1-21: Continue drug at usual dose
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Day 22: Stop drug
Start Quetiapine
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Day 1-4: approx. 25% of target dose
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Day 5-8: approx. 50% of target dose
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Day 9-12: approx. 75% of target dose
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Day 13: target dose
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Day 28: Reevaluate dose, if necessary adjust dose
More information
- During this switch you could monitor ECG, especially in patients prone to QT-conduction problems.
- There is a possibility of QT interval prolongation.[5]
— Partial agonist
— Quetiapine
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