Paliperidone ER-Zuclopenthixol MA

* This switch is intended for paliperidone long acting (Xeplion®, 30 days)

Paliperidone
long acting
Type Antipsychotic
Group Atypical AP
links
Medscape Paliperidone
PubChem 23724979
PubMed Paliperidone
Kompas (Dutch) Paliperidone
Wikipedia Paliperidone
Zuclopenthixol
Medium long acting
Type Antipsychotic
Group Thioxanthenes
links
PubChem 5311507
PubMed Zuclopenthixol
Kompas (Dutch) Zuclopenthixol
Wikipedia Zuclopenthixol

Switch medication from Paliperidone LA to Zuclopenthixol MA.

Nietinrijdenbord.png Stop Paliperidone LA
  • Day 1: Last depot injection
Eenrichtingbord.png Start Zuclopenthixol MA
  • Day 31: Start depot according general dosing advice
Infobord.png More information
  • During this switch you could monitor ECG, especially in patients prone to QT-conduction problems.
  • There is a possibility of QT interval prolongation.[1]
    Stopdepotstartafter30depot.jpg
Nietinrijdenbord.png — Paliperidone LA
Eenrichtingbord.png — Zuclopenthixol MA


  1. ↑ Stöllberger C, Huber JO, Finsterer J, Antipsychotic drugs and QT prolongation. Int Clin Psychopharmacol. 2005 Sep;20(5):243-51.
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