Paliperidone ER-Partial agonist
* This switch is intended for paliperidone long acting (Xeplion®, 30 days)
There are 3 different formulations of paliperidone extended release Xeplion® = Paliperidone long acting / 30 days Trivecta® = Paliperidone super long acting / 90 days Byannli® = Paliperidone ultra long acting / 178 days | ||||
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Switch medication from Paliperidone ER to Partial agonist.
Partial agonist is a collection of antipsychotic drugs having similar properties with respect to switching. A switch to member of the 'partial agonist' group from anotherdrug should be read as partial agonist-anotherdrug. Similarly, a switch from a member of the 'partial agonist' group to anotherdrug should be read as anotherdrug-partial agonist.
Stop Paliperidone ER
- Day 1: Last depot injection
Start Partial agonist
- Start drug at target dose on the day you would normally have injected the next depot.
More information
- During this switch you could monitor ECG, especially in patients prone to QT-conduction problems.
- There is a possibility of QT interval prolongation.[1]
— Paliperidone ER
— Partial agonist
— Partial agonist
- ↑ Stöllberger C, Huber JO, Finsterer J, Antipsychotic drugs and QT prolongation. Int Clin Psychopharmacol. 2005 Sep;20(5):243-51.
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