Switch medication from Olanzapine to Sertindole.
Stop Olanzapine
-
Day 1-4: approx. 75% of initial dose
-
Day 5-8: approx. 50% of initial dose
-
Day 9-12: approx. 25% of initial dose
-
Day 13: stop
Start Sertindole
-
Day 1-4: approx. 25% of target dose
-
Day 5-8: approx. 50% of target dose
-
Day 9-12: approx. 75% of target dose
-
Day 13: target dose
More information
- During this switch ECG monitoring is required because of possible QT-interval prolongation[4][5]
— Olanzapine
— Sertindole
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