Haloperidol LA-Paliperidone

Haloperidol
long acting
Type Antipsychotic
Group Butyrophenones
links
ATC-code N05AD01
Medscape Haloperidol
PubChem 3559
PubMed Haloperidol
Drugs.com haloperidol
Kompas (Dutch) Haloperidol
Wikipedia Haloperidol
Paliperidone
Type Antipsychotic
Group Atypical AP
links
Medscape Paliperidone
EMEA invega
PubChem 115237
PubMed Paliperidone
Kompas (Dutch) Paliperidone
Wikipedia Paliperidone

Switch medication from Haloperidol_LA to Paliperidone.

Nietinrijdenbord.png Stop Haloperidol_LA
  • Day 1: Last depot injection
Eenrichtingbord.png Start Paliperidone
  • Week 1-3: approx. 25% of target dose
  • Week 4-6: approx. 50% of target dose
  • Week 7-9: approx. 75% of target dose
  • Week 10: target dose
Infobord.png More information
  • During this switch you could monitor ECG, especially in patients prone to QT-conduction problems.
  • There is a possibility of QT interval prolongation.[4]
    StopDepotStartOral.jpg
Nietinrijdenbord.png — Haloperidol_LA
Eenrichtingbord.png — Paliperidone


  1. ↑ WHO Collaborating Centre for Drug Statistics Methodology ATC=N05AD01
  2. ↑ 2.02.1 The Lundbeck Institute; Psychotropics; Terminal Plasma Half-lives
  3. ↑ 3.03.1 Farmacotherapeutisch Kompas; Inleidende Tekst Antipsychotica (dutch)
  4. ↑ Stöllberger C, Huber JO, Finsterer J, Antipsychotic drugs and QT prolongation. Int Clin Psychopharmacol. 2005 Sep;20(5):243-51.
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