Haloperidol-Haloperidol LA
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Switch medication from Haloperidol to Haloperidol_LA.
Stop Haloperidol
- Week 1-3: approx. 75% of initial dose
- Week 4-6: approx. 50% of initial dose
- Week 7-9: approx. 25% of initial dose
- Week 10: stop
Start Haloperidol_LA
- Day 1: Start depot according general dosing advice (Dotted line in graph)
More information
- During this switch you could monitor ECG, especially in patients prone to QT-conduction problems.
- There is a possibility of QT interval prolongation.[6]
— Haloperidol
— Haloperidol_LA
— Haloperidol_LA
- ↑ WHO Collaborating Centre for Drug Statistics Methodology ATC=N05AD01
- ↑ 2.02.12.2 KNMP; Informatorium Medicamentorum 2015; Monografie "haloperidol" (Dutch)
- ↑ 3.03.13.23.3 The Lundbeck Institute; Psychotropics; Terminal Plasma Half-lives
- ↑ 4.04.14.24.3 Farmacotherapeutisch Kompas; Inleidende Tekst Antipsychotica (dutch)
- ↑ WHO Collaborating Centre for Drug Statistics Methodology ATC=N05AD01
- ↑ Stöllberger C, Huber JO, Finsterer J, Antipsychotic drugs and QT prolongation. Int Clin Psychopharmacol. 2005 Sep;20(5):243-51.
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