Duloxetine-bupropion
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Switch medication from duloxetine to bupropion.
Stop duloxetine
- Before day 1: gradually reduce dosage of duloxetine to a maximum of 60 mg/ day, when this dosage is > 60 mg/day.
- Day 1: reduce dosage of duloxetine to a maximum of 30 mg/day.
- Day 8: stop administration of duloxetine.
Start bupropion
- Day 1: simultaneously start bupropion in a normal dosage of 150 mg/day.
- Day 8: stop administration of duloxetine and continue bupropion.
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