Switch medication from dosulepine to imipramine.
Stop dosulepine
- Decrease with about 25% of the original dose per 3 days.
Start imipramine
- No wash-out period is needed.
- Increase with about 25% of target dose per 3 days.
More information
- Both drugs are a TCA with anticholinergic properties, so a switch to a relatively high starting dose can be made.
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