Combining-Olanzapine-Ziprasidone

Olanzapine
Type antipsychotic
Group atypical AP
Other use moodstabilizer
links
ATC-code N05AH03
Medscape Olanzapine
EMEA zyprexa
PubChem 4585
PubMed Olanzapine
Drugs.com olanzapine
Kompas (Dutch) Olanzapine
Wikipedia Olanzapine
Ziprasidone
Type Antipsychotic
Group Atypical AP
Other use Moodstabilizer
links
Medscape Ziprasidone
PubChem 60854
PubMed Ziprasidone
Wikipedia Ziprasidone

Adding ziprasidone to olanzapine.

Infobord.png General information
  • Olanzapine is principally metabolized by CYP1A2 and CYP2D6.
  • Ziprasidone is metabolized by CYP1A2 (minor) and CYP3A4.
Eenrichtingbord.png Start ziprasidone
  • The combination of these 2 antipsychotics seems to be irrational from a pharmacotherapeutical point of view.
Letopbord.png Cave
  • Agents with anticholinergic properties may have additive (side)effects when used in combination. [4]


  1. ↑ 1.01.11.21.3 KNMP; Informatorium Medicamentorum 2015; Monografie "olanzapine" (Dutch)
  2. ↑ Farmacotherapeutisch Kompas; Toxicologie (dutch)
  3. ↑ Woods SW Chlorpromazine equivalent doses for the newer atypical antipsychotics; J Clin Psychiatry 2003;64:663-667
  4. ↑ Interactions between ziprazidone and olanzapine on drugs.com
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