Switch medication from Aripiprazole LA to Clozapine.[1][2]
Stop Aripiprazole LA
-
Day 1: Last depot injection
Start Clozapine
-
Day 1: start with 12,5 mg at night
-
Day 2: 25 mg in divided doses
-
Day 3-15: increase daily dose every 1-2 day(s) with 25 mg
-
Day 16-28: if necessary, increase dose with 50-100 mg/week
- Low dose in the morning, high dose at night (twice daily dosage)
- Increments are dependent on the status of patient
More information
- More information you'll find in the summary of product characteristics (SPC) of aripiprazole depot injection. [3]
— Aripiprazole LA
— Clozapine
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