Agomelatine-maprotiline
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Switch medication from agomelatine to maprotiline.
Stop agomelatine
- Day 1: Stop agomelatine.
- Agomelatine can be stopped abruptly for every dosage.[1]
Start maprotiline
- Day 2: Start with normal dosage and increase with about 25% (up to 50%) every 3 days to target dose.
More information
- A wash-out period is not necessary.
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