Pimozide-Ziprasidone

Pimozide
Type Antipsychotic
Group Diphenylbutylpiperidines
links
Medscape Pimozide
PubChem 16362
PubMed Pimozide
Kompas (Dutch) Pimozide
Wikipedia Pimozide
Ziprasidone
Type Antipsychotic
Group Atypical AP
Other use Moodstabilizer
links
Medscape Ziprasidone
PubChem 60854
PubMed Ziprasidone
Wikipedia Ziprasidone

Switch medication from Pimozide to Ziprasidone.

Nietinrijdenbord.png Stop Pimozide
  • Day 1-4: approx. 75% of initial dose
  • Day 5-8: approx. 50% of initial dose
  • Day 9-12: approx. 25% of initial dose
  • Day 13: stop
Eenrichtingbord.png Start Ziprasidone
  • Day 1-4: approx. 25% of target dose
  • Day 5-8: approx. 50% of target dose
  • Day 9-12: approx. 75% of target dose
  • Day 13: target dose
Infobord.png More information
  • During this switch you could monitor ECG, especially in patients prone to QT-conduction problems.
  • There is a possibility of QT interval prolongation.[1]
    Switchstandaardup en down.jpg
Nietinrijdenbord.png — Pimozide
Eenrichtingbord.png — Ziprasidone


  1. Stöllberger C, Huber JO, Finsterer J, Antipsychotic drugs and QT prolongation. Int Clin Psychopharmacol. 2005 Sep;20(5):243-51.
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